After September Patch Tuesday, some environments are seeing Remote Desktop Services fail after a few minutes, hang at "Please wait for the Remote Desktop Configuration," with MMC/Explorer unresponsive and the Windows Update page stuck. Reports span Server 2012 and newer plus Windows 10/11. Microsoft published GPO mitigations; restarting VMs is a temporary bandage; rolling back removes the security fixes you just applied.
The same update wave is also tied to USB Audio Class 1.0 issues on recent Windows 11 builds and silent Excel paste failures after Office security updates — uninstalling the Office fix also uninstalls the security patches.
Ops rule for this week: don't mass-push to every RDS host on Monday morning. Stage a jump box and a terminal server, keep console/OOB access ready, tell helpdesk the known Excel/audio symptoms before tickets invent a ghost, and only then widen the ring.